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Ann Pharmacother. 2000 Apr;34(4):479-82.

Epididymo-orchitis following intravesical bacillus Calmette-Guérin therapy.

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  • 1South Dakota State University, Brookings, USA. Jennifer.menke@med.va.gov

Abstract

OBJECTIVE:

To describe a case of epididymo-orchitis that developed four years after treatment with intravesical bacillus Calmette-Guérin (BCG) and to review the incidence of this adverse effect.

DATA SOURCES:

Information about the patient was obtained from the medical chart. A MEDLINE search of English-language literature (from January 1976 to April 1999) was conducted.

STUDY SELECTION:

All case reports of BCG-related epididymo-orchitis were evaluated. Review articles describing complications of BCG therapy for bladder cancer and the prevention and treatment of these complications were reviewed.

DATA EXTRACTION:

Studies were evaluated for reports of BCG-related epididymo-orchitis and its treatment.

DATA SYNTHESIS:

Our case report is compared with others reported in the literature. The incidence of BCG-associated epididymoorchitis is rare.

CONCLUSIONS:

Epididymo-orchitis should be considered as a late complication of BCG therapy for bladder cancer. Proper patient selection may help decrease the risk of complications from BCG therapy.

PMID:
10772435
[PubMed - indexed for MEDLINE]
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