Schematic representation of the ARF GAP proteins. All have the ARF GAP domain (GAP, black) that includes the Zn-finger motif. ASAP1 and PAP also have a pleckstrin homology (PH) domain (PH, horizontal stripes), ankyrin repeats (Ank. Rep., diagonal stripes), a stretch of proline-rich sequences (PR), and an SH3 domain (SH3, gray). There are two forms of PAP, α and β, but one is shown for simplicity. The Git, Cat, and Pkl GAPs have proline-rich sequences, but no PH or SH3 domains. Asterisks denote that GAP activity for these proteins has not been demonstrated. Peripheral GAPs refers to ASAP1, PAP, Git1, Cat2, Pkl, and centaurin-α.