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Eur J Gastroenterol Hepatol. 1999 May;11(5):523-8.

Clinical relevance of antroduodenal manometry.

Author information

  • 1Gastrointestinal Motility Unit, University Hospital, Utrecht, The Netherlands. marcanne@knmg.nl

Abstract

OBJECTIVE:

To evaluate the outcome of antroduodenal manometry studies and their effect on the clinical treatment of patients.

DESIGN:

A retrospective review of clinical antroduodenal manometric studies performed between September 1990 and March 1997 (n = 109).

SETTING:

Tertiary referral centre.

MAIN OUTCOME MEASURES:

The predominant symptom, the indication for the study, the outcome and the clinical impact were scored. A positive impact was defined as an outcome that resulted in an alteration of the management of the patient (medication, surgery, feeding), established a new diagnosis, or resulted in new investigations or in referral to another specialist.

RESULTS:

Full records were obtained from 91 studies in 85 patients (mean age 43 years). Nausea and vomiting were the most predominant symptoms (37.4%). In 49.5% of the cases, the test was performed due to suspicion of a generalized motor disorder. A normal outcome was found in 37 studies. Non-specific motor abnormalities were reported in 72% of the studies with an abnormal outcome. Pseudo-obstruction was diagnosed in 20%. The manometric studies resulted in a new therapy in 12.6%, a new diagnosis in 14.9%, and referral to another specialist in 8%. A positive clinical impact was found in 28.7% of the patients.

CONCLUSION:

Antroduodenal manometry can be a helpful diagnostic technique in a specialized centre. More research is needed to gain insight into the significance of the large number of non-specific abnormalities that are often found.

PMID:
10755256
[PubMed - indexed for MEDLINE]
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