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Trends Microbiol. 2000 Apr;8(4):185-9.

The ins and outs of EBV infection.

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  • 1Depts of Medical Microbiology and Pathology, University of Edinburgh Medical School, Teviot Place, Edinburgh, UK EH8 9AG.


Epstein-Barr virus (EBV) infects almost the entire adult population of the world. The success of this virus appears to be based on its ability to infect the B cell, rather than any other cell type. We review EBV B-cell tropism, and discuss the mechanisms by which the virus may gain access to, and egress from, B cells in the normal host.

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