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    Bioorg Med Chem Lett. 2000 Mar 20;10(6):523-6.

    Design, synthesis and biological evaluation of 3-amino-3-phenylpropionamide derivatives as novel mu opioid receptor ligands.

    Allen MP, Blake JF, Bryce DK, Haggan ME, Liras S, McLean S, Segelstein BE.

    CNS Discovery, Central Research Division, Pfizer Inc, Groton, CT 06340, USA.

    3-Amino-3-phenylpropionamide derivatives were produced as small molecule mimics of the cyclic octapeptide octreotide from readily available imine 1. The compounds exhibit high affinity for the mu opioid receptor.

    PMID: 10741545 [PubMed - indexed for MEDLINE]

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