Pediatr Pulmonol. 2000 Apr;29(4):321-4.

Improvement of disseminated lymphangiomatosis with recombinant interferon therapy.

Laverdière C, David M, Dubois J, Russo P, Hershon L, Lapierre JG.

Source

Section of Hematology/Oncology, Division of Pediatrics, Ste-Justine Hospital, University of Montreal, Montreal, Canada.

Abstract

Disseminated lymphangiomatosis is a rare disorder with a poor prognosis. We present a case involving a 3-year-old boy who presented with pulmonary infiltrates, multiple lytic lesions of the ribcage, and small cystic lesions in the spleen. Open-lung and bone biopsies revealed disseminated lymphangiomatosis. Significant clinical and radiologic improvement were observed and persisted after 28 months of treatment with recombinant interferon alpha-2b (IFN alpha-2b). No significant toxicity has been observed.

PMID:: 10738021; [PubMed - indexed for MEDLINE]

Publication Types, MeSH Terms, Substances

Publication Types

Case Reports

MeSH Terms

Substances

LinkOut - more resources

Full Text Sources

Medical

Supplemental Content

Save items

Related citations in PubMed

Review Clinical improvement of diffuse lymphangiomatosis with pegylated interferon alfa-2b therapy: case report and review of the literature. [Pediatr Hematol Oncol. 2007]
Review Clinical improvement of diffuse lymphangiomatosis with pegylated interferon alfa-2b therapy: case report and review of the literature.
Ozeki M, Funato M, Kanda K, Ito M, Teramoto T, Kaneko H, Fukao T, Kondo N. Pediatr Hematol Oncol. 2007 Oct-Nov; 24(7):513-24.
Interferon alpha 2b treatment in an eleven-year-old boy with disseminated lymphangiomatosis. [Pediatr Blood Cancer. 2007]
Interferon alpha 2b treatment in an eleven-year-old boy with disseminated lymphangiomatosis.
Timke C, Krause MF, Oppermann HC, Leuschner I, Claviez A. Pediatr Blood Cancer. 2007 Jan; 48(1):108-11.
Recombinant interferon alfa 2b therapy in a patient with metastatic hepatocellular carcinoma. [J Clin Gastroenterol. 2002]
Recombinant interferon alfa 2b therapy in a patient with metastatic hepatocellular carcinoma.
Yuen MF, Hon C, Hui CK, Siu CW, Lai CL. J Clin Gastroenterol. 2002 Sep; 35(3):272-5.
Remission induced by interferon alfa in a patient with massive osteolysis and extension of lymph-hemangiomatosis: a severe case of Gorham-Stout syndrome. [J Pediatr Surg. 2005]
Remission induced by interferon alfa in a patient with massive osteolysis and extension of lymph-hemangiomatosis: a severe case of Gorham-Stout syndrome.
Takahashi A, Ogawa C, Kanazawa T, Watanabe H, Suzuki M, Suzuki N, Tsuchida Y, Morikawa A, Kuwano H. J Pediatr Surg. 2005 Mar; 40(3):E47-50.
Review Interferon alpha-2b at low doses as long-term antiangiogenic treatment of a metastatic intracranial hemangioendothelioma: a case report. [Oncol Rep. 2000]
Review Interferon alpha-2b at low doses as long-term antiangiogenic treatment of a metastatic intracranial hemangioendothelioma: a case report.
Palmieri G, Montella L, Martignetti A, Bianco AR. Oncol Rep. 2000 Jan-Feb; 7(1):145-9.

See reviews... See all...

Cited by 1 PubMed Central article

Lymphangioma in the epidural space of the thoracic spine. [J Korean Neurosurg Soc. 2010]
Lymphangioma in the epidural space of the thoracic spine.
Ha BY, Park JB, Kim YM, Lyo IU. J Korean Neurosurg Soc. 2010 May; 47(5):403-5. Epub 2010 May 31.

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Substance (MeSH Keyword)
PubChem chemical substance (submitted) records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.

Recent activity

Clear Turn Off Turn On

Improvement of disseminated lymphangiomatosis with recombinant interferon therap...
Improvement of disseminated lymphangiomatosis with recombinant interferon therapy.
Pediatr Pulmonol. 2000 Apr ;29(4):321-4.

PubMed
DNA methylation and cancer.
DNA methylation and cancer.
J Cell Physiol. 2000 May ;183(2):145-54.

PubMed
Third-body wear of cobalt-chromium-molybdenum implant alloys initiated by bone a...
Third-body wear of cobalt-chromium-molybdenum implant alloys initiated by bone and poly(methyl methacrylate) particles.
J Biomed Mater Res. 2000 Jun 5 ;50(3):322-30.

PubMed
Regulation of adenylyl cyclase, ERK1/2, and CREB by Gz following acute and chron...
Regulation of adenylyl cyclase, ERK1/2, and CREB by Gz following acute and chronic activation of the delta-opioid receptor.
J Neurochem. 2000 Apr ;74(4):1685-93.

PubMed
Using the World-Wide-Web to obtain feedback on the quality of surgical residency...
Using the World-Wide-Web to obtain feedback on the quality of surgical residency training.
Am J Surg. 2000 Jan ;179(1):74-5.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Result Filters

Display Settings:

Send to: