J Psychiatry Neurosci. 2000 Jan;25(1):14-23.

Functional activities of the amygdala: an overview.

Source

Dept. of Physiology, Instituto de Ciências Básicas da Saúde, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil. aarf@vortex.ufrgs.br

Abstract

Research to date into the amygdala shows that it has an integrative role in behavioural, vegetative and endocrine activities of animals in their relation with their environment. Animal studies show that amygdala has a role in emotional response, integrating input signals and initiating activities related to them. Different nuclei seem to have different effects. A complete picture of the functional roles of the amygdala is unavailable, and it has been suggested that the amygdala is functionally and anatomically heterogeneous. Amygdaloid subnuclei appear to have a role in the modulation of fear, in memory and attention, and in some sexual and sex-related behaviour of rats. In humans, functional magnetic resonance imaging shows that the amygdala responds preferentially to emotionally charged stimuli. Bilateral amygdala damage in humans can compromise the recognition of fear in facial expressions, an important ability in social judgement. Future study of the amygdala promises to shed light on emotional disorders in humans.

PMID:: 10721680; [PubMed - indexed for MEDLINE]
PMCID:: PMC1407702

Free PMC Article

Publication Types, MeSH Terms

Publication Types

MeSH Terms

LinkOut - more resources

Full Text Sources

Other Literature Sources

Labome Researcher Resource - ExactAntigen/Labome

Supplemental Content

Save items

Related citations in PubMed

Review Contributions of the amygdala to emotion processing: from animal models to human behavior. [Neuron. 2005]
Review Contributions of the amygdala to emotion processing: from animal models to human behavior.
Phelps EA, LeDoux JE. Neuron. 2005 Oct 20; 48(2):175-87.
Own-sex effects in emotional memory for faces. [Neurosci Lett. 2007]
Own-sex effects in emotional memory for faces.
Armony JL, Sergerie K. Neurosci Lett. 2007 Oct 9; 426(1):1-5. Epub 2007 Aug 22.
Review Sex differences in the responses of the human amygdala. [Neuroscientist. 2005]
Review Sex differences in the responses of the human amygdala.
Hamann S. Neuroscientist. 2005 Aug; 11(4):288-93.
Expression without recognition: contributions of the human amygdala to emotional communication. [Psychol Sci. 2000]
Expression without recognition: contributions of the human amygdala to emotional communication.
Anderson AK, Phelps EA. Psychol Sci. 2000 Mar; 11(2):106-11.
A process-specific functional dissociation of the amygdala in emotional memory. [J Cogn Neurosci. 2006]
A process-specific functional dissociation of the amygdala in emotional memory.
Sergerie K, Lepage M, Armony JL. J Cogn Neurosci. 2006 Aug; 18(8):1359-67.

See reviews... See all...

Cited by 4 PubMed Central articles

Disruption of maternal parenting circuitry by addictive process: rewiring of reward and stress systems. [Front Psychiatry. 2011]
Disruption of maternal parenting circuitry by addictive process: rewiring of reward and stress systems.
Rutherford HJ, Williams SK, Moy S, Mayes LC, Johns JM. Front Psychiatry. 2011; 2:37. Epub 2011 Jul 6.
Review Limbic structures and networks in children and adolescents with schizophrenia. [Schizophr Bull. 2008]
Review Limbic structures and networks in children and adolescents with schizophrenia.
White T, Cullen K, Rohrer LM, Karatekin C, Luciana M, Schmidt M, Hongwanishkul D, Kumra S, Charles Schulz S, Lim KO. Schizophr Bull. 2008 Jan; 34(1):18-29. Epub 2007 Oct 17.
Ultrastructural features of neurons and synaptic contacts in the posterodorsal medial amygdala of adult male rats. [J Anat. 2006]
Ultrastructural features of neurons and synaptic contacts in the posterodorsal medial amygdala of adult male rats.
Hermel EE, Faccioni-Heuser MC, Marcuzzo S, Rasia-Filho AA, Achaval M. J Anat. 2006 May; 208(5):565-75.

See all...

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
References for this PMC Article
Citation referenced in PubMed article. Only valid for PubMed citations that are also in PMC.
Free in PMC
Free full text articles in PMC
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.

Recent activity

Clear Turn Off Turn On

Functional activities of the amygdala: an overview.
Functional activities of the amygdala: an overview.
J Psychiatry Neurosci. 2000 Jan ;25(1):14-23.

PubMed
Borderline personality disorder and substance use disorders: a review and integr...
Borderline personality disorder and substance use disorders: a review and integration.
Clin Psychol Rev. 2000 Mar ;20(2):235-53.

PubMed
Applications of chromosomal fish in the Bovidae with emphases on physical mappin...
Applications of chromosomal fish in the Bovidae with emphases on physical mapping in domestic cattle and comparative cytogenetic analyses of the tribe Bovini.
Anim Biotechnol. 1999 ;10(3):105-8.

PubMed
d-Amphetamine in elderly patients refractory to rehabilitation procedures.
d-Amphetamine in elderly patients refractory to rehabilitation procedures.
J Am Geriatr Soc. 1979 Apr ;27(4):174-7.

PubMed
Magnetic resonance imaging in temporal lobe epilepsy: usefulness for the etiolog...
Magnetic resonance imaging in temporal lobe epilepsy: usefulness for the etiological diagnosis of temporal lobe epilepsy.
Neurol Med Chir (Tokyo). 2000 Jan ;40(1):1-15.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Result Filters

Display Settings:

Send to: