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Pediatr Neurosurg. 1999 Sep;31(3):159-62.

Medical management of eosinophilic granuloma of the cervical spine.

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  • 1Department of Neurosurgery, University of Pittsburgh Medical Center, Children's Hospital of Pittsburgh, PA 15213, USA.


We report a case of eosinophilic granuloma involving the vertebral bodies of the cervical spine in a 33-month-old girl. This lesion was diagnosed by needle biopsy and treated with prednisone and vinblastine therapy along with immobilization in a Minerva brace. The child has done well over a 9-month follow-up and has shown MRI evidence of resolution of the lesion, reestablishment of structural integrity within the cervical spine and potential reconstitution of the involved vertebral bodies.

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