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Arch Pathol Lab Med. 2000 Mar;124(3):411-5.

Esophageal collision tumor (Large cell neuroendocrine carcinoma and papillary carcinoma) arising in a Barrett esophagus.

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  • 1Department of Pathology and Laboratory Medicine, Mount Sinai Medical Center of Greater Miami, FL 33140, USA.


We report herein a unique case of an esophageal collision tumor composed of a papillary adenocarcinoma and a large cell neuroendocrine carcinoma arising in a Barrett esophagus. Hematoxylin-eosin and silver staining patterns, immunohistochemistry, and electron microscopy of the large cell neuroendocrine component are discussed.

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