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Clin Neurophysiol. 2000 Mar;111(3):413-6.

A new method to increase nociception specificity of the human blink reflex.

Author information

  • 1Institute of Neurology, The National Hospital for Neurology and Neurosurgery, Queen Square, London, UK. holgerk@ion.ucl.ac.uk

Abstract

OBJECTIVE:

The medullary R2 response of the blink reflex can be elicited by innocuous and noxious stimuli. The purpose of this study was to elicit a nociception specific R2 response with a new surface electrode.

METHODS:

In 10 healthy subjects the blink reflex was elicited using a standard (10-15 mA) and a new concentric surface electrode type (0.6-1.6 mA) which produces a pin-prick-like pain.

RESULTS:

After topical local anaesthesia with lignocaine/prilocaine R1 was unchanged, R2 was attenuated by 12% after standard stimulation but was almost abolished (-91%) with the new electrode type.

CONCLUSION:

Stimulation with low stimulus intensities but electrode-dependent high current density allows preferential depolarization of superficial nociceptive A-delta fibres. This new method is less traumatic than others and is useful in the study of trigeminal nociception.

PMID:
10699400
[PubMed - indexed for MEDLINE]
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