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Pediatrics. 2000 Mar;105(3):E36.

The highly protective effect of newborn circumcision against invasive penile cancer.

Author information

  • 1Department of Genetics, Pediatrics, Kaiser Permanente Medical Center, Oakland, California 94611-5693, USA. edgar.schoen@ncal.kaiperm.org

Abstract

OBJECTIVE:

We determined the relation between newborn circumcision and both invasive penile cancer (IPC) and carcinoma in situ (CIS) among adult male members of a large health maintenance organization.

SUBJECTS AND METHODS:

Circumcision status was ascertained by a combination of pathology reports, medical record review, and questionnaires for 213 adult male members of a large prepaid health plan who were diagnosed with IPC or CIS.

RESULTS:

Of 89 men with IPC whose circumcision status was known, 2 (2.3%) had been circumcised as newborns, and 87 were not circumcised. Of 118 men with CIS whose circumcision status was known, 16 (15.7%) had been circumcised as newborns.

CONCLUSIONS:

Our results confirm the highly protective effect of newborn circumcision against IPC and the less protective effect against CIS.

PMID:
10699138
[PubMed - indexed for MEDLINE]
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