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Acta Biochim Pol. 1999;46(3):717-20.

Anticoagulative effect of pepsin.

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  • 1Department of Instrumental Analysis, Medical Academy, BiaƂystok, Poland.

Abstract

Anticoagulative effect of pepsin is observed in vitro when its concentration is 36 microM and higher. This effect is due to inhibition of fibrin monomer polymerization. Protamine abolishes anticoagulative effect of pepsin. Pepsin does not influence platelet aggregation induced by ADP and collagen.

PMID:
10698279
[PubMed - indexed for MEDLINE]
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