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1: J Toxicol Clin Toxicol. 2000;38(1):55-7.Links

Massive ibuprofen ingestion with survival.

Seifert SA, Bronstein AC, McGuire T.

Rocky Mountain Poison and Drug Center, Denver, Colorado, USA. sseifert@pol.net

OBJECTIVE: To report a massive, 100 g ibuprofen ingestion in an adolescent, with survival. CASE REPORT: The patient developed coma, metabolic acidosis, and mild thrombocytopenia, but improved rapidly with supportive care. Renal function remained normal and no gastrointestinal bleeding occurred. CONCLUSIONS: Massive ingestion of ibuprofen may result in a variable picture with some elements of significant toxicity, but supportive care usually results in survival without sequelae.

PMID: 10696926 [PubMed - indexed for MEDLINE]

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