Your browser version may not work well with NCBI's Web applications. More information here...
1: Proc Natl Acad Sci U S A. 1976 Nov;73(11):3812-5.Click here to read Links

Nuclear magnetic resonance description of molecular motion and phase separations of cholesterol in lecithin dispersions.

Opella SJ, Yesinowski JP, Waugh JS.

Proton-enhanced 13C nuclear magnetic resonance is used to obtain signals from labeled cholesterols in lecithin dispersions. The [26-(13)C]cholesterol resonance indicates that the aliphatic tail of the molecule undergoes reorientation fast enough to average completely the chemical shift anisotropy. In contrast, [4-(13)C]cholesterol signals are characteristic of limited anisotropic reorientation. The resonances from the 4 position are sensitive to the temperature-concentration phase diagram. A phase boundary is observed at about 20 mole percent cholesterol.

PMID: 1069266 [PubMed - indexed for MEDLINE]

PMCID: PMC431220