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    J Nat Prod. 2000 Feb;63(2):173-5.

    Identification of deoxymiroestrol as the actual rejuvenating principle of "Kwao Keur", Pueraria mirifica. The known miroestrol may be an artifact.

    Chansakaow S, Ishikawa T, Seki H, Sekine (née Yoshizawa) K, Okada M, Chaichantipyuth C.

    Source

    Faculty of Pharmaceutical Sciences and Chemical Analysis Center, Chiba University, 1-33 Yayoi, Inage, Chiba 263-8522, Japan.

    Abstract

    Miroestrol (1) has been isolated previously as an active principle from "Kwao Keur" (Pueraria mirifica), a rejuvenating folk medicine from Thailand. Reinvestigation using bioassay-guided purification has resulted in the isolation of a new potent phytoestrogen, deoxymiroestrol (2). The facile aerial oxidation of 2 into 1 suggests the possibility that 1 may be an artifact.

    PMID:
    10691701
    [PubMed - indexed for MEDLINE]

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