Annu Rev Genet. 1999;33:261-311.

Ribosome synthesis in Saccharomyces cerevisiae.

Source

Department of Biochemistry and Molecular Biology, BioCentrum Amsterdam, Vrije Universiteit, The Netherlands.

Abstract

The synthesis of ribosomes is one of the major metabolic pathways in all cells. In addition to around 75 individual ribosomal proteins and 4 ribosomal RNAs, synthesis of a functional eukaryotic ribosome requires a remarkable number of trans-acting factors. Here, we will discuss the recent, and often surprising, advances in our understanding of ribosome synthesis in the yeast Saccharomyces cerevisiae. These will underscore the unexpected complexity of eukaryotic ribosome synthesis.

PMID:: 10690410; [PubMed - indexed for MEDLINE]

LinkOut - more resources

Full Text Sources

Supplemental Content

Save items

Related citations in PubMed

Review The accuracy center of a eukaryotic ribosome. [Biochem Cell Biol. 1995]
Review The accuracy center of a eukaryotic ribosome.
Liebman SW, Chernoff YO, Liu R. Biochem Cell Biol. 1995 Nov-Dec; 73(11-12):1141-9.
Review Synthesis of ribosomes in Saccharomyces cerevisiae. [Microbiol Rev. 1989]
Review Synthesis of ribosomes in Saccharomyces cerevisiae.
Warner JR. Microbiol Rev. 1989 Jun; 53(2):256-71.
Review Ribosome assembly in eukaryotes. [Gene. 2003]
Review Ribosome assembly in eukaryotes.
Fromont-Racine M, Senger B, Saveanu C, Fasiolo F. Gene. 2003 Aug 14; 313:17-42.
The role of nucleotide modifications in the yeast mitochondrial ribosome. [Nucleic Acids Symp Ser. 1995]
The role of nucleotide modifications in the yeast mitochondrial ribosome.
Sirum-Connolly K, Mason TL. Nucleic Acids Symp Ser. 1995; (33):73-5.
Regulation of ribosome biogenesis by the rapamycin-sensitive TOR-signaling pathway in Saccharomyces cerevisiae. [Mol Biol Cell. 1999]
Regulation of ribosome biogenesis by the rapamycin-sensitive TOR-signaling pathway in Saccharomyces cerevisiae.
Powers T, Walter P. Mol Biol Cell. 1999 Apr; 10(4):987-1000.

See reviews... See all...

Cited by over 100 PubMed Central articles

40S ribosome biogenesis co-factors are essential for gametophyte and embryo development. [PLoS One. 2013]
40S ribosome biogenesis co-factors are essential for gametophyte and embryo development.
Missbach S, Weis BL, Martin R, Simm S, Bohnsack MT, Schleiff E. PLoS One. 2013; 8(1):e54084. Epub 2013 Jan 30.
Multiple RNA interactions position Mrd1 at the site of the small subunit pseudoknot within the 90S pre-ribosome. [Nucleic Acids Res. 2013]
Multiple RNA interactions position Mrd1 at the site of the small subunit pseudoknot within the 90S pre-ribosome.
Segerstolpe Å, Granneman S, Björk P, de Lima Alves F, Rappsilber J, Andersson C, Högbom M, Tollervey D, Wieslander L. Nucleic Acids Res. 2013 Jan; 41(2):1178-90. Epub 2012 Nov 27.
Yeast Rrp8p, a novel methyltransferase responsible for m1A 645 base modification of 25S rRNA. [Nucleic Acids Res. 2013]
Yeast Rrp8p, a novel methyltransferase responsible for m1A 645 base modification of 25S rRNA.
Peifer C, Sharma S, Watzinger P, Lamberth S, Kötter P, Entian KD. Nucleic Acids Res. 2013 Jan; 41(2):1151-63. Epub 2012 Nov 23.

See all...

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
BioSystems
Pathways and biological systems (BioSystems) that cite the current articles. Citations are from the BioSystems source databases (KEGG and BioCyc).
Gene
Gene records that cite the current articles. Citations in Gene are added manually by NCBI or imported from outside public resources.
HomoloGene
HomoloGene clusters of homologous genes and sequences that cite the current articles. These are references on the Gene and sequence records in the HomoloGene entry.
Nucleotide (RefSeq)
NCBI nucleotide Reference Sequences (RefSeqs) that are cited in the current articles, included in the corresponding Gene Reference into Function, or that include the PubMed articles as references.
Nucleotide (Weighted)
Nucleotide records associated with the current articles through the Gene database. These are the related sequences on the Gene record that are added manually by NCBI.
Protein (RefSeq)
NCBI protein Reference Sequences (RefSeqs) that are cited in the current articles, included in the corresponding Gene Reference into Function, or that include the PubMed articles as references.
Protein (Weighted)
Protein records associated with the current articles through related Gene database records. These are the related sequences on the Gene record that are added manually by NCBI.
Substance (MeSH Keyword)
PubChem chemical substance (submitted) records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
Taxonomy via GenBank
Taxonomy records associated with the current articles through taxonomic information on related molecular database records (Nucleotide, Protein, Gene, SNP, Structure).
Domains
Conserved Domain Database (CDD) records that cite the current articles. Citations are from the CDD source database records (PFAM, SMART).
GEO Profiles
Gene Expression Omnibus (GEO) Profiles of molecular abundance data. The current articles are references on the Gene record associated with the GEO profile.
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.
Cited in Books
NCBI Bookshelf books that cite the current articles.

Recent activity

Clear Turn Off Turn On

Ribosome synthesis in Saccharomyces cerevisiae.
Ribosome synthesis in Saccharomyces cerevisiae.
Annu Rev Genet. 1999 ;33:261-311.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Result Filters

Display Settings:

Send to:

Ribosome synthesis in Saccharomyces cerevisiae.

Source

Abstract

Publication Types, MeSH Terms, Substances, Grant Support

Publication Types

MeSH Terms

Substances

Grant Support

LinkOut - more resources

Full Text Sources

Other Literature Sources

Molecular Biology Databases

Research Materials

Supplemental Content

Save items

Related citations in PubMed

Cited by over 100 PubMed Central articles

Related information

Recent activity

Simple NCBI Directory

Getting Started

Resources

Popular

Featured

NCBI Information