The study reported in this article is a secondary analysis of data collected from a random sample of 124 Cambodian adults, ages 18 to 76 years. Participants were interviewed about their mental health status and factors associated with a diagnosis of posttraumatic stress disorder (PTSD) or major depression. From analysis of the data, the following risk factors were identified with PTSD and depression: experiencing a greater number of war traumas increased the risk of both PTSD and major depression; experiencing a greater number of resettlement stressors during the past year increased the risk of both PTSD and major depression; and having financial stress increased the risk of major depression.