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Proc Natl Acad Sci U S A. 2000 Feb 29;97(5):2379-84.

Arabidopsis cytochrome P450s that catalyze the first step of tryptophan-dependent indole-3-acetic acid biosynthesis.

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  • 1Department of Biology, Boston University, 5 Cummington Street, Boston, MA 02215, USA.

Abstract

Plants synthesize numerous secondary metabolites that are used as developmental signals or as defense against pathogens. Tryptophan (Trp)-derived secondary metabolites include camalexin, indole glucosinolates, and indole-3-acetic acid (IAA); however, the steps in their synthesis from Trp or its precursors remain unclear. We have identified two Arabidopsis cytochrome P450s (CYP79B2 and CYP79B3) that can convert Trp to indole-3-acetaldoxime (IAOx), a precursor to IAA and indole glucosinolates.

PMID:
10681464
[PubMed - indexed for MEDLINE]
PMCID:
PMC15809
Free PMC Article

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