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Int J Epidemiol. 1999 Dec;28(6):1102-9.

Adult nutrient intake as a risk factor for Parkinson's disease.

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  • 1Department of Biostatistics and Research Epidemiology, Henry Ford Health System, Detroit, Michigan, USA.

Abstract

BACKGROUND:

This population-based case-control study evaluated nutrient intake as a risk factor for Parkinson's disease (PD) among people aged > or =50 years in metropolitan Detroit.

METHODS:

Cases (n = 126) were diagnosed between 1991 and 1995 and neurologist-confirmed. Controls (n = 432) were frequency-matched for sex, age (+/-5 years) and race. Using a standardized food frequency questionnaire, subjects reported the foods they ate within the past year.

RESULTS:

Estimating the association between PD and risk of being in the highest versus the lowest intake quartile, there were elevated odds ratios for total fat (OR 1.94, 95% confidence interval [CI] : 1.05-3.58), cholesterol (OR 2.11, 95% CI: 1.14-3.90), lutein (OR 2.52, 95% CI: 1.32-4.84) and iron (OR 1.88, 95% CI: 1.05-3.38).

CONCLUSIONS:

These results suggest an association of PD with high intake of total fat, saturated fats, cholesterol, lutein and iron.

PMID:
10661654
[PubMed - indexed for MEDLINE]
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