Anim Biotechnol. 1999;10(1-2):1-13.

Sperm cell mediated transgenesis: a review.

Source

Division of Molecular & Life Sciences, University of Abertay Dundee, Scotland.

Abstract

Transgenesis would be greatly streamlined if sperm cells could be used as transgene vectors. Attempts to 'force' sperm cells to take up transgenes may be more worthy of further study than 'autouptake' attempts. However, thorough proof of its effectiveness will be required if sperm cell-mediated gene transfer is to be accepted, given the evolutionary implications associated with the possibility of sperm cells being able to transfer exogenous DNA.

PMID:: 10654426; [PubMed - indexed for MEDLINE]

Publication Types, MeSH Terms

Publication Types

Review

MeSH Terms

LinkOut - more resources

Full Text Sources

Supplemental Content

Save items

Related citations in PubMed

Review Electroporation of salmon sperm for gene transfer: efficiency, reliability, and fate of transgene. [Mol Reprod Dev. 2000]
Review Electroporation of salmon sperm for gene transfer: efficiency, reliability, and fate of transgene.
Sin FY, Walker SP, Symonds JE, Mukherjee UK, Khoo JG, Sin IL. Mol Reprod Dev. 2000 Jun; 56(2 Suppl):285-8.
Review New gene transfer methods. [Theriogenology. 2002]
Review New gene transfer methods.
Wall RJ. Theriogenology. 2002 Jan 1; 57(1):189-201.
Effect of transgene concentration, flanking matrix attachment regions, and RecA-coating on the efficiency of mouse transgenesis mediated by intracytoplasmic sperm injection. [Biol Reprod. 2007]
Effect of transgene concentration, flanking matrix attachment regions, and RecA-coating on the efficiency of mouse transgenesis mediated by intracytoplasmic sperm injection.
Moreira PN, Pérez-Crespo M, Ramírez MA, Pozueta J, Montoliu L, Gutiérrez-Adán A. Biol Reprod. 2007 Feb; 76(2):336-43. Epub 2006 Oct 11.
In vivo gene transfer into the testis by electroporation and viral infection--a novel way to study testis and sperm function. [Soc Reprod Fertil Suppl. 2007]
In vivo gene transfer into the testis by electroporation and viral infection--a novel way to study testis and sperm function.
Parrington J, Coward K, Hibbitt O, Kubota H, Young C, McIlhinney J, Jones O. Soc Reprod Fertil Suppl. 2007; 65:469-74.
In vivo gene transfer by electroporation allows expression of a fluorescent transgene in hamster testis and epididymal sperm and has no adverse effects upon testicular integrity or sperm quality. [Biol Reprod. 2006]
In vivo gene transfer by electroporation allows expression of a fluorescent transgene in hamster testis and epididymal sperm and has no adverse effects upon testicular integrity or sperm quality.
Hibbitt O, Coward K, Kubota H, Prathalingham N, Holt W, Kohri K, Parrington J. Biol Reprod. 2006 Jan; 74(1):95-101. Epub 2005 Sep 14.

See reviews... See all...

Cited by 3 PubMed Central articles

Review Transgenesis procedures in Xenopus. [Biol Cell. 2008]
Review Transgenesis procedures in Xenopus.
Chesneau A, Sachs LM, Chai N, Chen Y, Du Pasquier L, Loeber J, Pollet N, Reilly M, Weeks DL, Bronchain OJ. Biol Cell. 2008 Sep; 100(9):503-21.
Gene Therapy: The Potential Applicability of Gene Transfer Technology to the Human Germline. [Int J Med Sci. 2004]
Gene Therapy: The Potential Applicability of Gene Transfer Technology to the Human Germline.
Smith KR. Int J Med Sci. 2004; 1(2):76-91. Epub 2004 Jun 1.
Effective generation of transgenic pigs and mice by linker based sperm-mediated gene transfer. [BMC Biotechnol. 2002]
Effective generation of transgenic pigs and mice by linker based sperm-mediated gene transfer.
Chang K, Qian J, Jiang M, Liu YH, Wu MC, Chen CD, Lai CK, Lo HL, Hsiao CT, Brown L, et al. BMC Biotechnol. 2002 Apr 19; 2:5. Epub 2002 Apr 19.

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.

Recent activity

Clear Turn Off Turn On

Sperm cell mediated transgenesis: a review.
Sperm cell mediated transgenesis: a review.
Anim Biotechnol. 1999 ;10(1-2):1-13.

PubMed
Management of peritoneal-surface malignancy: the surgeon's role.
Management of peritoneal-surface malignancy: the surgeon's role.
Langenbecks Arch Surg. 1999 Dec ;384(6):576-87.

PubMed
Testing the extent of sequence similarity among viroids, satellite RNAs, and hep...
Testing the extent of sequence similarity among viroids, satellite RNAs, and hepatitis delta virus.
J Mol Evol. 2000 Jan ;50(1):98-102.

PubMed
Differential nuclear localization and nuclear matrix association of the splicing...
Differential nuclear localization and nuclear matrix association of the splicing factors PSF and PTB.
J Cell Biochem. 2000 Jan ;76(4):559-66.

PubMed
Evidence for integration of Glyptapanteles indiensis polydnavirus DNA into the c...
Evidence for integration of Glyptapanteles indiensis polydnavirus DNA into the chromosome of Lymantria dispar in vitro.
Virus Res. 2000 Jan ;66(1):27-37.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Result Filters

Display Settings:

Send to: