Science. 1999 Dec 24;286(5449):2524-5.

Linkage disequilibrium and recombination in hominid mitochondrial DNA.

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Institute of Cell, Animal and Population Biology, University of Edinburgh, Edinburgh EH9 1JT, UK.

Abstract

The assumption that human mitochondrial DNA is inherited from one parent only and therefore does not recombine is questionable. Linkage disequilibrium in human and chimpanzee mitochondrial DNA declines as a function of the distance between sites. This pattern can be attributed to one mechanism only: recombination.

Comment in

Human genetics. mtDNA shows signs of paternal influence. [Science. 1999]
Human genetics. mtDNA shows signs of paternal influence.Strauss E. Science. 1999 Dec 24; 286(5449):2436.

Comment on

Questioning evidence for recombination in human mitochondrial DNA. [Science. 2000]
Questioning evidence for recombination in human mitochondrial DNA.Parsons TJ, Irwin JA. Science. 2000 Jun 16; 288(5473):1931.
Questioning evidence for recombination in human mitochondrial DNA. [Science. 2000]
Questioning evidence for recombination in human mitochondrial DNA.Jorde LB, Bamshad M. Science. 2000 Jun 16; 288(5473):1931.
Questioning evidence for recombination in human mitochondrial DNA. [Science. 2000]
Questioning evidence for recombination in human mitochondrial DNA.Kivisild T, Villems R. Science. 2000 Jun 16; 288(5473):1931.
Questioning evidence for recombination in human mitochondrial DNA. [Science. 2000]
Questioning evidence for recombination in human mitochondrial DNA.Kumar S, Hedrick P, Dowling T, Stoneking M. Science. 2000 Jun 16; 288(5473):1931.

PMID:: 10617471; [PubMed - indexed for MEDLINE]

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