Format

Send to:

Choose Destination
See comment in PubMed Commons below
Curr Opin Microbiol. 1999 Dec;2(6):582-7.

How bacteria talk to each other: regulation of gene expression by quorum sensing.

Author information

  • 1Department of Molecular Biology, Princeton University, Princeton, 08544-1014, USA. bbassler@molbiol.princeton.edu

Abstract

Quorum sensing, or the control of gene expression in response to cell density, is used by both gram-negative and gram-positive bacteria to regulate a variety of physiological functions. In all cases, quorum sensing involves the production and detection of extracellular signalling molecules called autoinducers. While universal signalling themes exist, variations in the design of the extracellular signals, the signal detection apparatuses, and the biochemical mechanisms of signal relay have allowed quorum sensing systems to be exquisitely adapted for their varied uses. Recent studies show that quorum sensing modulates both intra- and inter-species cell-cell communication, and it plays a major role in enabling bacteria to architect complex community structures.

PMID:
10607620
[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science
    Loading ...
    Write to the Help Desk