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    Curr Biol. 1999 Dec 2;9(23):R876-8.

    Ringing changes to the 'bell-shaped curve'.

    Bootman MD, Lipp P.

    Laboratory of Molecular Signalling, The Babraham Institute, Babraham, CB2 4AT, UK.

    The 'bell-shaped' curve relating cytosolic Ca(2+) concentration to IP(3) receptor activation is considered important in the generation of the complex Ca(2+) signals seen inside many cells. But recent findings suggest this bimodal relationship is not always evident and may not apply to some IP(3) receptor isoforms.

    PMID: 10607554 [PubMed - indexed for MEDLINE]

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