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Trends Microbiol. 1999 Dec;7(12):488-93.

Mutation as an origin of genetic variability in Helicobacter pylori.

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  • 1Dept of Medical Microbiology and Immunology, University of Alberta, Edmonton, Alberta, Canada T6G 2H7. gw4@gpu.srv.ualberta.ca

Abstract

The availability of two complete Helicobacter pylori genome sequences and recent studies of its population genetics have provided a detailed picture of genetic diversity in this important human gastric pathogen. It is believed that, in addition to genetic recombination, de novo mutation could have a role in generating the high level of genetic variation in H. pylori.

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PMID:
10603484
[PubMed - indexed for MEDLINE]
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