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Curr Opin Biotechnol. 1999 Dec;10(6):595-603.

Production of fine chemicals using biocatalysis.

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  • 1Institute of Biotechnology, Research Center Juelich, Juelich, 52425, Germany.


Presently, a large number of biotransformations are carried out on an industrial scale and are discussed in a fast increasing number of reviews. Besides this, a significant number of biotransformations have been investigated over the past year, from degrading to transforming and synthetic reactions. The development of more specific and stable biocatalysts, either isolated enzymes or whole cells, generated by the new methods of genetic engineering and improved by reaction engineering have led to new industrial biotransformations.

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