Arch Ital Urol Androl. 1999 Sep;71(4):249-51.

[Transurethral alprostadil (MUSE) in erectile dysfunction].

[Article in Italian]

Source

Divisione di Urologia e Andrologia, Ospedale S. Anna, Como, Italia.

Abstract

The ideal therapy for erectile dysfunction should be easy, non invasive, painless, with a high success and a low side effects rate. Alternative methods of delivery drugs to the erectile body, instead of intracavernosal injection of vasoactive drugs such as prostaglandin, have been evaluated. Vasoactive agents can be administered topically into the urethral mucosa for absorption into the corpus spongiosum and transfer into the corpora cavernosa via small communicating veins. We report data from the literature and our experience with MUSE (Medicated Urethral System for Erection) for the treatment of erectile dysfunction. Penile pain or discomfort is the common adverse effect reported, while no priapism of fibrotic complication is reported. But local discomfort, limited efficacy, and cost are to be considered.

PMID:: 10592541; [PubMed - indexed for MEDLINE]

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Review [Transurethral alprostadil administration with MUSE ("Medicated Urethral System for Erection"). Current overview and personal experiences]. [Urologe A. 1998]
Review [Transurethral alprostadil administration with MUSE ("Medicated Urethral System for Erection"). Current overview and personal experiences].
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