Nucleic Acids Res. 2000 Jan 1;28(1):270-2.

The SYSTERS protein sequence cluster set.

Source

Deutsches Krebsforschungszentrum, Theoretische Bioinformatik, Im Neuenheimer Feld 280, D-69120 Heidelberg, Germany. a.krause@dkfz-heidelberg.de

Abstract

The SYSTERS (short for SYSTEmatic Re-Searching) protein sequence cluster set consists of the classification of all sequences from SWISS-PROT and PIR into disjoint protein family clusters and hierarchically into superfamily and subfamily clusters. The cluster set can be searched with a sequence using the SSMAL search tool or a traditional database search tool like BLAST or FASTA. Additionally a multiple alignment is generated for each cluster and annotated with domain information from the Pfam database of protein domain families. A taxonomic overview of the organisms covered by a cluster is given based on the NCBI taxonomy. The cluster set is available for querying and browsing at http://www.dkfz-heidelberg. de/tbi/services/cluster/systersform

PMID:: 10592244; [PubMed - indexed for MEDLINE]
PMCID:: PMC102384

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Research Support, Non-U.S. Gov't

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Proteins

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