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Nucleic Acids Res. 2000 Jan 1;28(1):231-4.

SMART: a web-based tool for the study of genetically mobile domains.

Author information

  • 1EMBL, Meyerhofstrasse1, 69012 Heidelberg, Germany.

Abstract

SMART (a Simple Modular Architecture Research Tool) allows the identification and annotation of genetically mobile domains and the analysis of domain architectures (http://SMART.embl-heidelberg.de ). More than 400 domain families found in signalling, extra-cellular and chromatin-associated proteins are detectable. These domains are extensively annotated with respect to phyletic distributions, functional class, tertiary structures and functionally important residues. Each domain found in a non-redundant protein database as well as search parameters and taxonomic information are stored in a relational database system. User interfaces to this database allow searches for proteins containing specific combinations of domains in defined taxa.

PMID:
10592234
[PubMed - indexed for MEDLINE]
PMCID:
PMC102444
Free PMC Article

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