Format

Send to:

Choose Destination
See comment in PubMed Commons below
Clin Infect Dis. 1999 Dec;29(6):1561-3.

Acute lung injury in leptospirosis: clinical and laboratory features, outcome, and factors associated with mortality.

Author information

  • 1Intensive Care Unit, Instituto de Infectologia Emilio Ribas, Universidade de São Paulo, São Paulo, Brazil.

Abstract

Forty-two consecutive patients with leptospirosis and acute lung injury who were mechanically ventilated were analyzed in a prospective cohort study. Nineteen patients (45%) survived, and 23 (55%) died. Multivariate analysis revealed that 3 variables were independently associated with mortality: hemodynamic disturbance (odds ratio [OR], 6.0; 95% confidence interval [CI], 0.9-38.8; P=. 047), serum creatinine level >265.2 micromol/L (OR, 10.6; 95% CI, 0. 9-123.7; P =.026), and serum potassium level >4.0 mmol/L (OR, 19.9; 95% CI, 1.2-342.8; P=.009). These observations can be used to identify factors associated with mortality early in the course of severe respiratory failure in leptospirosis.

PMID:
10585813
[PubMed - indexed for MEDLINE]
Free full text
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for HighWire
    Loading ...
    Write to the Help Desk