If the loop fits.

Nat Struct Biol. 1999 Dec;6(12):1081-3. doi: 10.1038/70002.

Abstract

The structure of the yeast L30 ribosomal protein bound to its autoregulatory RNA site has been determined by NMR spectroscopy. The intricate architecture of the RNA internal loop and the structure of the binding region of the protein both are stabilized in the complex, highlighting the importance of mutually-induced fit in RNA-protein interactions.

Publication types

  • News
  • Comment

MeSH terms

  • Base Sequence
  • Binding Sites
  • Fungal Proteins / chemistry
  • Fungal Proteins / metabolism
  • Models, Molecular
  • Nuclear Magnetic Resonance, Biomolecular
  • Nucleic Acid Conformation
  • Protein Conformation
  • RNA, Fungal / chemistry*
  • RNA, Fungal / genetics
  • RNA, Fungal / metabolism*
  • Ribosomal Protein L3
  • Ribosomal Proteins / chemistry*
  • Ribosomal Proteins / metabolism*
  • Saccharomyces cerevisiae / chemistry*
  • Saccharomyces cerevisiae / genetics

Substances

  • Fungal Proteins
  • RNA, Fungal
  • Ribosomal Protein L3
  • Ribosomal Proteins