Display Settings:

Format

Send to:

Choose Destination
Exp Cell Res. 1999 Nov 25;253(1):117-30.

Signaling via vascular endothelial growth factor receptors.

Author information

  • 1Molecular/Cancer Biology Laboratory, Haartman Institute, University of Helsinki, Helsinki, Finland.

Abstract

Angiogenesis, or development of blood vessels from preexisting vasculature, has important functions under both normal and pathophysiological conditions. Vascular endothelial growth factor receptors 1-3, also known as flt-1, KDR, and flt-4, are endothelial cell-specific receptor tyrosine kinases which serve as key mediators of the angiogenic responses. The review focuses on the signaling pathways that are initiated from these receptors and the recently identified VEGF coreceptor neuroplilin-1.

Copyright 1999 Academic Press.

PMID:
10579917
[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science
    Loading ...
    Write to the Help Desk