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Can J Psychiatry. 1999 Oct;44(8):811-3.

Psychotic side effects of psychostimulants: a 5-year review.

Author information

  • 1Department of Psychiatry, Royal University Hospital, Saskatoon, Saskatchewan. cherland@duke.usask.ca



To examine the rate of psychotic and mood-congruent psychotic side effects of stimulant medications in children treated for attention-deficit hyperactivity disorder (ADHD).


A chart review was completed of all children diagnosed with ADHD in an outpatient clinic from January 1989 to March 1995.


Over 5 years, 192 children were diagnosed with ADHD. Ninety-eight children received treatment at the clinic with stimulants. Six children developed psychotic or mood-congruent psychotic symptoms during treatment. Children on medication were followed for an average of 1 year and 9 months.


Awareness of the potential for psychotic side effects from stimulant medications is important when prescribing for children. A large prospective study would be useful to predict the frequency and classification of the side effects in children.

[PubMed - indexed for MEDLINE]
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