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Lancet. 1999 Oct 30;354(9189):1524-5.

Immunoassay for urothelial cancers that detects DNA replication protein Mcm5 in urine.


Cancer-screening tests for internal organs are severely constrained by low specificity or sensitivity, cost, and morbidity. We report a non-invasive immunofluorometric assay for detection of urothelial cancers based on ectopic expression of the DNA replication protein Mcm5.

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