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Psychiatr Clin North Am. 1999 Sep;22(3):609-27, ix.

Substance abuse and bipolar comorbidity.

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  • 1Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston, USA.


Bipolar disorder and substance abuse commonly co-occur. In fact, as many as 50% of individuals with bipolar disorder have been found to have a lifetime history of substance abuse or dependence. This article discusses the very important comorbidity of bipolar disorder as it is complicated by substance abuse, focusing on the prevalence, course, diagnostic considerations and treatment.

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