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Am J Ophthalmol. 1999 Sep;128(3):387-9.

Postpartum cerebellar herniation in von Hippel-Lindau syndrome.

Author information

  • 1Oncology Service, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA.

Abstract

PURPOSE:

To describe exacerbation during pregnancy of cerebellar hemangioblastoma in von Hippel-Lindau syndrome.

METHOD:

Case-report. A 21-year-old woman with von Hippel-Lindau syndrome was found on routine ocular examination to have severe papilledema 1 week after giving birth.

RESULTS:

Immediate magnetic resonance imaging disclosed a large cerebellar cyst from hemangioblastoma causing cerebellar tonsillar herniation. Immediate neurosurgical intervention was life saving.

CONCLUSION:

Worsening of intracranial hemangioblastoma during pregnancy in cases of von Hippel-Lindau syndrome should be realized and periodic neurologic and ophthalmologic observation is warranted.

PMID:
10511048
[PubMed - indexed for MEDLINE]
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