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Curr Biol. 1999 Sep 23;9(18):R691-4.

Bidirectional signals establish boundaries.

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  • 1European Molecular Biology Laboratory Meyerhofstrasse 1, 69117, Heidelberg, Germany. klein@embl-heidelberg.de

Abstract

Recent studies have shown that the formation of boundaries between the segments - rhombomeres - of the vertebrate hindbrain depends on bidirectional signalling between neighbouring cells. This signalling is mediated by Eph receptors and their ligands, which has been found to restrict cell intermingling in vitro.

PMID:
10508605
[PubMed - indexed for MEDLINE]
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