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Trends Microbiol. 1999 Oct;7(10):410-3.

The mar regulon: multiple resistance to antibiotics and other toxic chemicals.

Author information

  • 1Center for Adaptation Genetics and Drug Resistance, Dept of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston, MA 02111, USA.

Abstract

The chromosomal multiple antibiotic resistance (mar) locus of Escherichia coli and other members of the Enterobacteriaceae controls resistance to multiple, structurally unrelated compounds including antibiotics, household disinfectants, organic solvents and other toxic chemicals. The Mar phenotype is induced following exposure to a variety of chemicals with aromatic rings.

PMID:
10498949
[PubMed - indexed for MEDLINE]
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