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Neurology. 1999;53(5 Suppl 2):S9-12.

Evidence supporting the temporal lobe epilepsy personality syndrome.

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  • 1Department of Psychiatry, University of Tennessee Medical School, Memphis 38105, USA.


A deepening of emotionality with a serious, highly ethical, and spiritual demeanor has been described by clinicians as a positive personality change among patients with chronic mesial temporal lobe epilepsy. Some of these patients tend to be particularly orderly and detailed in their speech and actions (viscosity) and often experience a relative decrease in sexual interest and arousal. These personality changes, distinct from personality changes noted in any other individuals, are subtle in the majority of patients with chronic epilepsy. Patients with the described personality changes may also develop intermittent symptoms of an interictal dysphoric disorder, with episodes of irritable moods that contrast with a predominantly good-natured attitude and for which the patients will be remorseful. The Bear-Fedio Inventory needs to be further modified before it can serve as an adequate instrument for assessing the prevailing personality changes and the intermittent dysphoric symptoms.

[PubMed - indexed for MEDLINE]
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