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Pharm Sci Technolo Today. 1999 Aug;2(8):311-320.

Differential scanning calorimetry: applications in drug development.

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  • 1Merck Frosst Canada & Co., PO Box 1005, Pointe Claire-Dorval, QC, Canada H9R 4P8.


Differential scanning calorimetry (DSC) is frequently the pharmaceutical thermal analysis technique of choice because of its ability to provide detailed information about both the physical and energetic properties of a substance. This review provides an up-to-date overview of the applications of DSC in the drug development process. It should serve as a broad introduction to those starting work in this area, and also as a valuable reference for those already practising in this field.

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