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Nucleosides Nucleotides. 1999 Apr-May;18(4-5):885-9.

L-purine nucleosides as selective antimalarials.

Author information

  • 1School of Biochemistry and Molecular Genetics, University of New South Wales, Sydney, Australia.

Abstract

L-nucleosides selectively enter malaria infected erythrocytes and have the unique ability to be metabolised by the malarial adenosine deaminase. This has allowed us to design novel L-nucleosides as potential anti-malarials.

PMID:
10432703
[PubMed - indexed for MEDLINE]
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