Nat Struct Biol. 1999 Aug;6(8):714-6.

Probing plant polyketide biosynthesis.

Abstract

The first structure of a chalcone synthase has been determined. Enzymes in this family have broad substrate specificities and participate in the biosynthesis of many secondary plant products, including compounds that provide defense against pathogens and precursors to the bitter acids in hops that flavor beer.

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