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Eur J Dermatol. 1999 Jul-Aug;9(5):354-6.

Rothmund-Thomson syndrome with herpes encephalitis.

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  • 1Department of Dermatology, Hamamatsu University School of Medicine, 3600 Handa-cho, Hamamatsu 431-3192, Japan. itoutai@hama-med.ac.jp

Abstract

A 4-year-old Japanese boy with Rothmund-Thomson syndrome suffered from severe herpes encephalitis at 5 months of age. The serum level of immunoglobulin G was low and the responsiveness of peripheral blood mononuclear cells to bacterial superantigens was poor. It was suggested that these immunological abnormalities, possibly associated with Rothmund-Thomson syndrome, led to severe infection with herpes simplex virus in our patient.

PMID:
10417436
[PubMed - indexed for MEDLINE]
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