[Spinal tumors in infancy. A report of 48 cases]

Rev Neurol. 1999 May;28(9):863-7.
[Article in Spanish]

Abstract

Introduction: Spinal tumours in infancy are an infrequent oncological disorder. The clinical features, usually of insidious onset, are alterations in gait and a painful spine.

Objective: To analyze the different histological types of spinal tumours seen in infancy and their form of presentation in our series.

Patients and methods: We reviewed the clinical histories of 48 patients with intraspinal tumours, aged under 15 years, whose reports of histological diagnosis had been sent to our centre.

Results: Of the patients studied, 17 were girls (35.4%) and 31 boys (64.6%) with an average age of 7.7 years. The histological diagnoses made most frequently were astrocytomas (22.9%) and lipomas (18.8%) followed by metastases (12.5%), ependymomas (8.3%) and Edwing's sarcoma (8.3%). The clinical features were present prior to diagnosis for between 1 and 6 months in 13 patients, and for less than one month in 9 patients. The presenting symptoms were alterations in gait and back pain in most patients. Exploratory tests were related to the involvement of long vias and second motor-neurone lesions. The main topographical findings were: in the axial plane the lesions were extradural (23 patients) and in the sagittal plane there was dorsal involvement (34 patients).

Conclusions: Insidious, progressive alterations in gait together with continuous, nocturnal back pain are valuable data when a serious spinal disorder is to be suspected. Early diagnosis should be based on neuroimaging tests, essentially MR, in the patients in whom spinal cord involvement is considered.

Publication types

  • English Abstract

MeSH terms

  • Adolescent
  • Astrocytoma / complications
  • Astrocytoma / pathology*
  • Back Pain / diagnosis
  • Back Pain / etiology
  • Child
  • Child, Preschool
  • Diagnosis, Differential
  • Ependymoma / complications
  • Ependymoma / pathology*
  • Female
  • Humans
  • Infant
  • Infant, Newborn
  • Lipoma / complications
  • Lipoma / pathology*
  • Magnetic Resonance Imaging
  • Male
  • Movement Disorders / diagnosis
  • Movement Disorders / etiology
  • Retrospective Studies
  • Sarcoma / complications
  • Sarcoma / pathology*
  • Spinal Neoplasms / complications
  • Spinal Neoplasms / pathology*