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Atherosclerosis. 1999 May;144(1):237-49.

The antiatherosclerotic effect of Allium sativum.

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  • 1Institute for Transfusion Medicine and Immunohematology, University Clinic Charité of the Humboldt University, Berlin, Germany.

Abstract

In a randomized, double-blind, placebo-controlled clinical trial, the plaque volumes in both carotid and femoral arteries of 152 probationers were determined by B-mode ultrasound. Continuous intake of high-dose garlic powder dragees reduced significantly the increase in arteriosclerotic plaque volume by 5-18% or even effected a slight regression within the observational period of 48 months. Also the age-dependent representation of the plaque volume shows an increase between 50 and 80 years that is diminished under garlic treatment by 6-13% related to 4 years. It seems even more important that with garlic application the plaque volume in the whole collective remained practically constant within the age-span of 50-80 years. These results substantiated that not only a preventive but possibly also a curative role in arteriosclerosis therapy (plaque regression) may be ascribed to garlic remedies.

PMID:
10381297
[PubMed - indexed for MEDLINE]
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