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EMBO J. 1999 Jun 15;18(12):3187-92.

Gastrulation in Drosophila: the logic and the cellular mechanisms.

Author information

  • Institut für Genetik, Universität zu Köln, Weyertal 121, D-50931 Köln, Germany. mleptin@uni-koeln.de

Abstract

The egg contains a set of molecules that can be used to trigger cell-shape changes leading to morphogenetic movements. The temporally and spatially controlled activation of these molecules, and hence the choreography of gastrulation movements, is determined by region-specific expression of transcription factors which turn on a set of downstream targets whose products mediate the successive steps of gastrulation.

PMID:
10369659
[PubMed - indexed for MEDLINE]
PMCID:
PMC1171399
Free PMC Article
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