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    J Child Psychol Psychiatry. 1999 May;40(4):537-49.

    Quasi-autistic patterns following severe early global privation. English and Romanian Adoptees (ERA) Study Team.

    Rutter M, Andersen-Wood L, Beckett C, Bredenkamp D, Castle J, Groothues C, Kreppner J, Keaveney L, Lord C, O'Connor TG.

    MRC Child Psychiatry Unit and Social Genetic and Developmental Psychiatry Research Centre, Institute of Psychiatry, London, UK.

    Six per cent of child in a sample of 111 children who were adopted into U.K. families from Romania, and who were systematically assessed at the ages of 4 and 6 years, showed autistic-like patterns of behaviour. A further 6% showed milder (usually isolated) autistic features. Such autistic characteristics were not found in a similarly studied sample of 52 children adopted in the first 6 months of life within the U.K. The children from Romania with autistic patterns showed clinical features closely similar to "ordinary" autism at 4 years but they differed with respect to the improvement seen by age 6 years, to an equal sex ratio, and to a normal head circumference. The children from Romania with autistic features tended to differ from the other Romanian adoptees with respect to a greater degree of cognitive impairment and a longer duration of severe psychological privation.

    PMID: 10357161 [PubMed - indexed for MEDLINE]

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