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Ann Pathol. 1999 Apr;19(2):119-23.

[An unusual variant of urothelial carcinoma: the "nested variant of urothelial carcinoma." Report of two cases].

[Article in French]

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  • 1Service d'Anatomie pathologique, Hôpital Bretonneau, Faculté de médecine, Tours.


We report two cases of a poorly known variant of transitional cell carcinoma, the "nested variant of urothelial carcinoma". This tumor is composed of small islands or nests of transitional cells, presenting little atypia and mimicking von Brünn's nests. This low grade tumoral variant seems to behave as a high grade tumor of the same stage. Deep biopsies are necessary to display tumoral invasion, which allows the diagnosis. Importance of the knowledge of this entity is highlighted in order to avoid misdiagnoses that could delay appropriate therapy.

[PubMed - indexed for MEDLINE]
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