Abstract
Glial cells play fundamental roles in neurogenesis. In addition, defective or abnormal gliogenesis is associated with severe diseases. To understand the molecular basis of such diseases, it is crucial to identify the genes promoting normal gliogenesis. Here we identify GCMB, which encodes a human protein homologous to the fly glial promoting factor glial cell deficient/glial cell missing (glide/gcm).
Publication types
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Comparative Study
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Research Support, Non-U.S. Gov't
MeSH terms
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Amino Acid Sequence
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Animals
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Base Sequence
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Chromosome Mapping
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Chromosomes, Human, Pair 6 / genetics
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DNA / genetics
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DNA Primers / genetics
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DNA-Binding Proteins
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Drosophila Proteins
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Drosophila melanogaster / genetics
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Evolution, Molecular
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Gene Expression
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Genes, Insect
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Humans
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In Situ Hybridization, Fluorescence
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Mice
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Molecular Sequence Data
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Neuroglia / cytology
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Neuropeptides / genetics*
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Nuclear Proteins
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Sequence Homology, Amino Acid
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Species Specificity
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Trans-Activators / genetics*
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Transcription Factors
Substances
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DNA Primers
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DNA-Binding Proteins
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Drosophila Proteins
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GCM protein, Drosophila
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GCM2 protein, human
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Neuropeptides
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Nuclear Proteins
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Trans-Activators
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Transcription Factors
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DNA