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Curr Opin Microbiol. 1999 Apr;2(2):153-8.

Regulation of the heat-shock response.

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  • 1HSP Research Institute, Kyoto Research Park, Shimogyo-ku, Kyoto, 600-8813, Japan. tyura@hsp.co.jp


Current models of both heat induction and the chaperone-mediated feedback control of the sigma32 regulon in Escherichia coli have been further substantiated, and the extent of conservation among Gram-negative bacteria has been assessed. Analyses of the 'CIRCE' and other regulons or operons in Gram-positive and Gram-negative bacteria have provided new insights into their significance and regulatory mechanisms.

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