Phenolic compounds from Duchesnea chrysantha and their cytotoxic activities in human cancer cell

Arch Pharm Res. 1994 Dec;17(6):476-9. doi: 10.1007/BF02979129.

Abstract

Five phenolic compounds were isolated from 80% aq. acetone extract of Duchesnea chrysantha. Their cytotoxicities were screened by the colorimetric tetrazolium assay (MTT assay). Gallic acid, methyl caffeate, protocatechuic acid and pedunculagin mildly inhibited the survival of PC14 and MKN45 human cancer cell. Brevifolin carboxylic acid showed a strong cytotoxic activity.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antineoplastic Agents, Phytogenic / isolation & purification*
  • Antineoplastic Agents, Phytogenic / pharmacology
  • Drug Screening Assays, Antitumor
  • Humans
  • Hydrolyzable Tannins / isolation & purification
  • Hydrolyzable Tannins / pharmacology
  • Phenols / isolation & purification*
  • Phenols / pharmacology
  • Plants, Medicinal / chemistry*
  • Tumor Cells, Cultured

Substances

  • Antineoplastic Agents, Phytogenic
  • Hydrolyzable Tannins
  • Phenols